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Search Results for " neurodegenerative disorder "

10

Compounds

Cat No. Product Name Synonyms Targets
T13486 Neurodegenerative Disorder-Targeting Compound 1 Others
Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].
T21883 Gedunin HSP
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Gedunin is an Hsp90 inhibitor, and inhibits ovarian cancer cell proliferation.
T83527 (Rac)-Neurodegenerative Disorder-Targeting Compound 1
(Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.
T24265 KMS88009 KMS 88009,KMS-88009
KMS88009 is an amyloid-β aggregation inhibitor that acts by ameliorating neurodegenerative disorder.
T61578 BRD3731
BRD3731 is a selective inhibitor of GSK3β, demonstrating an IC50 value of 15 nM for GSK3β and 215 nM for GSK3α. Due to its inhibitory properties, BRD3731 holds promise for investigating various medical conditions, includ...
T75751 β-Amyloid (1-40) (TFA)
β-Amyloid (1-40) TFA, a principal protein in plaques observed in the brains of Alzheimer's disease patients [1], is pivotal in research focused on this neurodegenerative disorder.
T35804 C16 Lactosylceramide (d18:1/16:0)
C16 Lactosylceramide is an endogenous bioactive sphingolipid. It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Pla...
T35809 C20 Sphingomyelin (d18:1/20:0)
C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin and in human plasma where it is positively correlate...
T73289 MHTT-IN-1
mHTT-IN-1 (Example 1) is a potent inhibitor of the mutant huntingtin protein (mHTT), which is toxic and primarily responsible for Huntington's disease (HD), an inherited autosomal dominant neurodegenerative disorder. Thi...
T37191 Mu-6S-Palm-β-Glc
Mu-6S-Palm-β-Glc is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. Mu-6S-...
TargetMol